Services

Our service workflows

The VIB Single Cell Core provides state-of-the-art services and expertise for researchers seeking to implement single cell omics workflows into their daily research. Our integrated approach spans the multi-disciplinary nature of single cell experiments, from tissue to data. The researcher gets the full range of  services through one facility as we support and coordinate every step of the workflow. All projects are tracked within a custom Laboratory Information Systems (LIMS) giving full traceability of your project. Our commitment is to provide a straightforward and seamless experience, keeping you up to date as we progress.

With different single-cell omics platforms in our portfolio, there is always a solution that suits your needs. Cherry-pick the services and support you need to meet your research goals and to work within your budget.

Image
Concept

Consulting, design and project planning

Text

Every tissue is different, just as every research question. During the intake of your experiment, we help design a single-cell omics experiment tailored to your research needs and coordinate further project planning. We have built a strong profiency in setting up well-balanced experimental plans in a cost-effective way. When necessary, we bring other experts from the VIB single-cell community to the table according  to the needs of the specific project.

Image
Single Cell Workflow

Sample preparation assistance

Text

We will guide you through the selection (or optimization) of a suitable cell/nuclei isolation method. If required, we coordinate FACS-based sorting through the flow core facilities. We will be at your side in the lab to assist throughout the single cell isolation and assess sample/cell quality together.

Image
Single Cell Workflow

Single cell library generation and sequencing

Text

Our service pipeline covers library preparation, pooling and sequencing. Through extensive use of laboratory automation, we save time, reduce sample-to-sample variability and decrease human error. Our experts apply all necessary QC checks throughout every stage of the process to ensure the most optimal library and sequencing quality.

Sequencing modalities are available in-house at VIB (Illumina NextSeqX, HiSeqX and NovaSeq6000 at VIB Nucleomics Core)

Image
Single Cell Workflow

Data management

Text

We add several layers of data pre-processing and analysis beyond the raw data delivery, including comprehensive analysis and quality reports. After data generation and delivery, we will help you outline the next steps to kick-start your single-cell journey.
We can store and keep track of your data until you need it for your publications. It is our mission to include a complementary data management service that meet the demands of FAIR principles.

Image
Single Cell Workflow

Bioinformatics tools and training

Text

We help you interpret and analyze your data by offering expertise, software tools and training. Together with an application-specific report, an interactive analysis and visualization tool helps you to get familiar with your data.

Access our single cell training programs and online e-learning platform aimed at both molecular biologists and bioinformaticians. The programs consist of modules with different focusses ranging from data pre-processing, quality control, CITEseq, differential gene expression, visualizations, cell-cell communication, spatial transcriptomics and much more.

Image
Single Cell Workflow

Bioinformatics consulting services

Text

We are currently preparing to expand our bioinformatics consulting services, to offer dedicated and project-specific support in data mining.

As a researcher, I could rely on one single team and facility from start to finish. Tapping into coordinated pipelines saved me time and money, allowing me to focus on my science projects.
Stijn Vanhee
Dr. Stijn Vanhee
Senior Postdoctoral Scientist Ghent University
The streamlined workflows overcome major roadblocks that molecular biologists are often confronted with when moving towards single-cell studies.
GeertBerx
Prof. Dr. Geert Berx
Group leader at Cancer Research Institute Ghent
The VIB Single Cell Core is offering a fast sample-to-data solution that meets the research goals of my lab, for both small pilot experiments and large-scale projects.
Bert De Rybel
Prof. Dr. Bert De Rybel
Group leader at Center for Plant Systems Biology (VIB-UGent)